---
title: "DepMap - Cancer Dependency Map - Air Market"
description: "If you are asking whether a gene is worth going after in cancer, someone has already measured what happens when it is knocked out across many cell lines. This queries that resource for dependency sco…"
canonical: "https://airmarket.ai/app/depmap"
---

[Air Market](/) / [Research](/category/research) / DepMap - Cancer Dependency Map

Skill by [K-Dense](/@k-dense-ai)

# DepMap - Cancer Dependency Map

Find out which genes a cancer cell line cannot live without

## What this does

If you are asking whether a gene is worth going after in cancer, someone has already measured what happens when it is knocked out across many cell lines. This queries that resource for dependency scores, drug sensitivity, and gene effect profiles. Reach for it when you want evidence before committing to a target.

### Top 3 things it does for you

- Look up gene dependency scores for a cell line
- Check drug sensitivity across cell lines
- Pull the gene effect profile for a target

## Information

**DepMap - Cancer Dependency Map at a glance**

|  |  |
| --- | --- |
| Kind | Skill |
| Publisher | [K-Dense](/@k-dense-ai) |
| Category | [Research](/category/research) |
| Works with | Agent Skills - an open standard supported by 40+ agents |
| Version | 1.0 |
| Size | 17 KB |
| Licence | MIT |
| Repository | [k-dense-ai/scientific-agent-skills](https://github.com/k-dense-ai/scientific-agent-skills/tree/93124850ef08487e423165554c54f0b333d5631d/skills/depmap) |
| GitHub stars | 34,239 (as of Nov 2026) |

## Security report

**Verified.** AIR scanned this exact version of DepMap - Cancer Dependency Map and flagged nothing. AIR's verdict: **safe**.

**What DepMap - Cancer Dependency Map's check was run against**

|  |  |
| --- | --- |
| Commit | 93124850ef08487e423165554c54f0b333d5631d |
| Content hash | b558e25d3bde37487c1d30963707ce6bd4967faf0b0899a783c84d47a5ed0ec2 |
| Files read | [Browse the files at this exact commit](https://github.com/k-dense-ai/scientific-agent-skills/blob/93124850ef08487e423165554c54f0b333d5631d/skills/depmap/SKILL.md) |

A scan is named by the exact content it read, not by a version number. A different version is a different artifact, and nothing here applies to a version AIR has not scanned.

[Read the full security report for DepMap - Cancer Dependency Map](/security/depmap)

## About DepMap - Cancer Dependency Map

This queries the Cancer Dependency Map for cancer cell line gene dependency scores from CRISPR Chronos, drug sensitivity data, and gene effect profiles.

Use it to identify cancer-specific vulnerabilities, look for synthetic lethal interactions, and validate oncology drug targets.

## What's inside

- SKILL.md - instructions
- references/dependency_analysis.md - reference

## Questions

### Is DepMap - Cancer Dependency Map safe to install?

AIR scanned this exact version of DepMap - Cancer Dependency Map and flagged nothing. AIR's verdict: safe. The verdict is named by the content that was read, at commit 93124850ef08, so it cannot drift onto a version nobody scanned. The full report is at https://airmarket.ai/security/depmap.

### How do I install DepMap - Cancer Dependency Map?

Open https://airmarket.ai/app/depmap on Air Market and use the install action: Air Market hands Claude a prompt naming this exact skill, and Claude sets it up. Source, pinned to the exact commit this listing describes: https://github.com/k-dense-ai/scientific-agent-skills/tree/93124850ef08487e423165554c54f0b333d5631d/skills/depmap. Install from that link, not the branch.

## Related on Air Market

- [More Research listings](/category/research)
- [Everything by K-Dense](/@k-dense-ai)

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Canonical URL: <https://airmarket.ai/app/depmap>